International Plant & Animal Genome Conference / PAG 32 • January 10-15, 2025  •  San Diego, CA, USA

g.coruzzi 160Carroll & Milton Petrie Professor of Biology, NYU Center for Genomics & Systems Biology, NY, USA
Tuesday, January 16, 8:00 AM / Town & Country Ballroom

Talk Title:  “The 4th Dimension of Gene Regulatory Networks: TIME.”


Dr. Gloria Coruzzi is currently the Carroll & Milton Petrie Professor at New York University’s Center for Genomics and Systems Biology.  Her research in Systems Biology combines genomic, bioinformatic and system biology approaches to identify gene networks involved in dynamic transcriptional regulatory mechanisms.  Her recent studies exploit time - the 4th and largely unexplored dimension of transcriptional networks - to temporally perturb transcription factor function, and to model dynamic gene regulatory networks that can predict network states at future time-points, the ultimate goal of systems biology. The dynamic gene regulatory networks uncovered have revealed new biology associated with nitrogen nutrient signaling in plants including a “Hit-and-Run” mode of dynamic transcription.   Most recently, a “just-in-time” analysis of time-series transcriptome data has uncovered an otherwise hidden transcriptional logic cascade that underlies nitrogen signaling and use in plants.  Importantly, these time-based analysis approaches can be used to uncover the temporal “transcriptional logic” for any biological response system in any organism.  Dr. Coruzzi’s research is funded by the National Institutes of Health, The National Science Foundation, and the Department of Energy.  Dr. Coruzzi was named an American Association for the Advancement of Science Fellow in 2005, a Fellow of the American Society of Plant Biology (ASPB) in 2010, was awarded the ASPB Stephen Hales Prize in 2016.  She currently serves on several editorial and scientific advisory boards including The Arabidopsis Information Portal (AIP) and the DOE Joint Genome Institute (JGI) Plant Program Advisory Board.


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